منابع مشابه
Heat-Shock Proteins in Autoimmunity
1 Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201, USA 2Department of Academic Rheumatology, King’s College, London SE1 1UL, UK 3Department of Cellular and Developmental Biology (STEMBIO), University of Palermo, Viale delle Scienze, 90128 Palermo, Italy 4Department of Neurology and Neuromuscular Reference Center, Ghent University Hospita...
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Heat-shock proteins as antigens in autoimmunity Willem van Eden,* Els J. M. Hogervorst,* Marca H. M. Wauben,* Ruurd van der Zee,t and Claire, J. P. Boog* *Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, University of Utrecht, Yalelaan I, 8508 TD Utrecht, The Netherlands and +Department of Bacteriology, National Institute for Public Health and Environmental Hygi...
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Heat shock proteins (HSPs) have been linked to the therapy of both cancer and inflammatory diseases, approaches that utilize contrasting immune properties of these proteins. It would appear that HSP family members Hsp60 and Hsp70, whether from external sources or induced locally during inflammation, can be processed by antigen-presenting cells and that HSP-derived epitopes then activate regulat...
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Epigenetic alterations, including DNA acetylation, hypermethylation and hypomethylation, and the associated transcriptional changes of the affected genes are central to the evolution and progression of various human cancers, including pancreatic cancer. Cancer-associated epigenetic alterations are attractive therapeutic targets because such epigenetic alterations, unlike genetic changes, are po...
متن کاملHeat shock and the heat shock proteins.
As all biologists appreciate, there is constant interaction between life and the environment, and temperature plays a critical role. It establishes distribution limits, it affects rates of function as well as the survival of organisms. Notoriously sensitive to temperature is plant growth. Critical steps in plant life such as germination, flowering and breaking of dormancy can be manipulated by ...
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ژورنال
عنوان ژورنال: Autoimmune Diseases
سال: 2013
ISSN: 2090-0422,2090-0430
DOI: 10.1155/2013/621417